Five authoritative scientists including Linda Partridge, founding director of the Max Planck Institute for Aging in Germany, have updated and improved the cellular aging markers based on aging research in the past 10 years, published in the top science journal

The field of aging research has identified 12 markers that represent different organisms common features of aging. Stem cell exhaustion sign: stem cell regeneration

Stem cells are mysterious and mysterious to most people Strangeness has also been infinitely exaggerated. But, if this magical object is so subtle, let's appreciate its elegance.

What are stem cells? Where are stem cells found in the human body?

Stem cells are capable of self-replication, multi-directional differentiation and homing Potential primitive cells are the origin cells of the body and the ancestor cells that form various tissues and organs of the human body. Just like a tree trunk, it can grow branches, leaves, flowers and fruits.

Nowadays, scientists have successfully isolated stem cells from many organs or tissues. These include retinal stem cells, pancreatic stem cells, osteoblast stem cells, etc. Research shows that stem cells not only exist in embryos, but also in adults. Corresponding stem cells can be isolated from umbilical blood, umbilical cord, placenta, bone marrow, fat, blood and other tissues.

Where do stem cells come from?

During the process of cell differentiation, due to the regulation in the cytoplasm The uneven distribution of differentiation proteins causes a daughter cell to irreversibly move towards the end of differentiation and become a differentiated cell with specialized functions, until it completely loses the ability to divide again and eventually senescence and death.

In order to make up for this deficiency, the body retains some undifferentiated primitive cells. This maintains the characteristics of the parent generation. These retained undifferentiated primitive cells are called stem cells. Once physiological needs are met, these stem cells can divide to produce differentiated cells according to the developmental pathway.

But the number of stem cells in our body decreases with age. Will lead to reduced regeneration capacity.

What is the task of stem cells?

The task of stem cells is to make unlimited copies It has the characteristics of producing a large number of working cells so that human organs can work normally. Scientists summarize the five major tasks of stem cells, referred to as 5R:

Replace Replace or supplement

Repair Patch or repair

Regenerate tissue and organ regeneration< /strong>

Restore the restoration or restoration of life functions

Regress degeneration of cancer cells

Theoretically, if 5R can function normally, the body will not get sick, age, or even die.

Causes and manifestations of aging?

The root cause of human aging and the appearance of wrinkles is cellular Aging and reduction, which are basically caused by stem cell aging. Stem cells are seed cells used to replace various tissue cells and are the production products of human cells. Aging of stem cell populations severely weakens their ability to proliferate and differentiate. The replenishment capacity of new cells is insufficient, and aging cells cannot be replaced in time, resulting in a decline in body function and people getting older every day.

Why can stem cells fight aging?

In the entire life activities of a person's life, the cells of the body are constantly In the process of new cells replacing aging and degenerated cells, when the cell renewal rate is lower than the cell aging rate, insufficient renewal occurs, and the body will age. It manifests as a decline in systemic system functions, slow metabolism, and the appearance of aging.

The cells in the body that can play a role in renewal are stem cells, and the source of aging It’s the insufficient number of stem cells.

Top 10 of 12 signs of cellular anti-aging: stem cell failure

Stem cells have the unique ability to turn into many different types of cells. Because of this, they can replenish cells as they die. However, the number of stem cells in our body decreases with age, which results in reduced regenerative capacity.

Replenishing stem cells is particularly important at this time.

What are the effects of stem cells on the human body?

1. Stem cells can accelerate the metabolism of lipoproteins, thereby It can effectively reduce the concentration of triglycerides, cholesterol and low-density lipoprotein in the blood, and prevent diseases such as hyperlipidemia and hypertension.

2. Stem cells can resist aging and improve Alzheimer's disease.

3. Stem cells can prevent skin from sagging and sagging, thereby reducing skin wrinkles and making The skin becomes elastic. Stem cells can improve immunity and make the body less susceptible to disease.

4. Support stem cell renewal: Stem cells are a type of self-renewal and multi-directional Cells with differentiation potential can differentiate into a variety of functional cells under certain conditions.

5. Improve neuron formation and cognition: It can also be used to treat neurological disorders Systemic diseases, such as motor neuron disease, Parkinson's disease, sequelae of cerebral infarction, etc.

6. Anti-aging and cell regeneration: The role of stem cells is to use their own differentiation potential to achieve the purpose of tissue regeneration and repair.

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